Presentations | Publications
Dr. Borgert presented “Hypothesis-driven weight of evidence framework for evaluating data in the context of the U.S. EPA’s Endocrine Disruptor Screening and Testing Program. Endocrine Disruptors, 2nd International Conference. Die Akademie Fresenius, Frankfurt, Germany, June 7-8, 2011.
Dr. Borgert presented “What is “Scientific Quality” and How Do We Judge It?” Plenary Lecture, CropLife America Science Forum: Judging the Quality of Scientific Work. Washington, DC. May 13, 2011.
Borgert, CJ. The Intersection of Design and Interpretation of Mixtures Data. 50th Annual Meeting of the Society of Toxicology, Washington, DC, March 6, 2011.
Sargent, EV., Golden, RJ., Dietrich, DR, Casella, G. McCarty, LS, Borgert, CJ. “The Human Relevant Potency Threshold: Uncertainty Analysis and Human Calibration for Risk Assessment.” Poster presented at the 50th Annual Meeting of the Society of Toxicology, Washington, DC, March 6, 2011.
Borgert, CJ. Setting the Scene for the Mixtures Discussion. European Chemical Industry Council (Cefic), Brussels, Belgium. December 16, 2010
Borgert, CJ. Weight of Evidence. 2010 Endocrine Workshop, EDSP Compliance, National Institutes of Health, Bethesda, MD, December 13, 2010.
Borgert, CJ. Uncertainty vs Certainty in Cumulative Toxicology. “Risk Assessment in the 21st Century: Cumulative Risk Sub-Team” ILSI, Brussels, Belgium, October 21-22, 2010.
Borgert, CJ. Uncertainty vs. Certainty in Cumulative Risk Assessment: Anti-Androgens. Testimony before the Consumer Product Safety Commission’s Chemical Hazard Assessment Panel on Phthalates, Washington, D.C., July 26, 2010.
Borgert, CJ. Comments on Concept Paper by Prof. D.R. Dietrich: Courage for Simplification and Imperfection in the 21st Century Assessment of “Endocrine Disruption.” CAAT Workshop, 21st Century Validation Strategies for 21st Century Tools”, July 13-14, 2010, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Video of panel discussion is available JHSPH website
Borgert, CJ. Objective or Subjective? Should the Scientist be Judged? Society for Risk Analysis Annual Meeting, December 6-9, 2009, Baltimore, Maryland.
Borgert, CJ. Experimental Evaluation of Interactions: Pitfalls and Challenges. The 41st Annual Symposium, Society of Toxicology of Canada, Montreal, Quebec, Nov 29-Dec 1, 2009.
Dr. Borgert was faculty in a continuing education course, Current Approaches in Mixture Risk, at the Society of Toxicology, Continuing Education Program, 47th Annual Meeting, March 15-19, 2009, Baltimore, Maryland. Dr. Borgert presented a lecture on “Relative Potency Factors in Drug Safety Assessment.”
Borgert, CJ. National Academy of Sciences workshop on Characterizing the Potential Human Toxicity from Low Doses of Pharmaceuticals in Drinking Water: Are New Risk Assessment Methods or Approaches Required? Considerations for Single Chemical vs Mixture Risk Assessment December 11-12, 2008, Washington, D.C.
Borgert, CJ. EPA Science Advisory Panel review of the Endocrine Tier 1 Screens/Battery. Washington D.C. March 25-March 28, 2008.
Borgert, CJ. Cumulative Risk: The Case Against Estrogen Equivalents. Session III, ISRTP workshop, Conducting and Assessing the Results of Endocrine Screening. February 19-20, 2008. Lister Hill Center Auditorium, NIH. Bethesda, MD.
Borgert, CJ. Regulatory Assessment of Chemical Mixtures: Concepts & Caveats. Symposium IV: Combination Toxicology. American College of Toxicology (ACT), 28th Annual Meeting. Charlotte, NC. November 12, 2007.
Borgert, CJ. Food-Drug Interactions, Theory and case studies. Institute of Food Technologists (IFT) Annual Meetings, Symposium entitled: Health Food Ingredients: When is a food really a drug? July 29, 2007, Chicago, IL.
Ulloa, S., Findley, KC., Casella, G. , Borgert, CJ. Evaluation of Adverse Event Sampling Bias. Cosmetic, Toiletry, and Fragrance Association meeting "Adverse Health Effects: Managing Reports for Cosmetics & OTC Drugs." June 14, 2007.
Borgert, CJ. Interpretation of mixtures data - case studies of the good, the bad, and the ugly. Society of Toxicology Continuing Education Program, 46th Annual Meeting, March 25-29, 2007, Charlotte, NC.
Ulloa S, Findley KC, Casella G, & Borgert CJ. 2007. Evaluation of adverse event sampling bias. Society of Toxicology Annual Meeting, March 25-29, 2007, Charlotte, NC.
Findley KC, & Borgert CJ. 2007. Evaluation of a novel relative potency approach for an herbal dietary supplement. Society of Toxicology Annual Meeting, March 25-29, 2007, Charlotte, NC.
Borgert CJ, Guiney PD, Casella G, & Shiverick KT. 2006. Biological plausibility and application to risk assessment: Human relevance and dose response analysis. Society of Toxicology Annual Meeting, March 5-9, 2006, San Diego, CA.
Borgert CJ. 2006. Perspectives on development and use of screens and tests for endocrine activity. Chemical Producers & Distributors Association, Mid-Year Meeting February 27 – March 1, 2006. Arlington, VA.
Borgert CJ, Findley KC, Ulloa S, Borgert SA. 2005. Causality Assessment of Herbal-Drug Interactions: Scientific Data vs. Diagnostic Scales. Presentation for the International Conference on Quality and Safety Issues Related to Botanicals, Sponsored by CFSAN/FDA and International Society for Horticultural Sciences. National Center for Natural Products Research, August 15 – 18, University, MS.
Borgert CJ. 2005. Causality Assessment: Is There a Role for Biomonitoring? Presentation for ISRTP Workshop: Understanding Human Biomonitoring. June 16, 2005. Hyatt Regency, Sacramento, CA.
Casella G, Hobert J, Booth J. 2005. Clustering using objective functions and stochastic search. Presentation for the Biostatistics Seminar, Harvard University, May 2005, Cambridge, MA.
Borgert CJ. 2005. Can Mode of Action Predict Toxicity for Mixtures Risk Assessment? Presentation for Workshop Session: Dose-Additivity of Mixtures: Where Are We Going With The Science? SOT Annual Meeting, March 7, 2005, New Orleans, LA.
Borgert CJ, Guiney PD, Casella G, Shiverick KT. 2005. Polyomics: A revolution in mechanistic risk assessment? Abstract / Poster presented at SOT Annual Meeting, March 7, 2005, New Orleans, LA.
Borgert CJ. 2005. Interactivity Toxicity – Information from Pharmacodynamics and Toxicokinetics to Predict Interactions. Presentation for SOT Contemporary Concepts In Toxicology Workshop: Charting the Future: Building the Scientific Foundation for Mixtures Joint Toxicity and Risk Assessment. Crowne Plaza Ravinia, February 16–17, 2005, Atlanta, GA.
Casella G. 2005, Jan. & Oct. Basic design principles for (microarray) statistical experiments. Presented at the University of Florida, Gainesville, FL.
Borgert CJ & Findley KC. 2005. Synergism, Antagonism, or Additivity of Dietary Supplements with Hemostasis and Antithrombotic Therapies. Presentation for National Institutes of Health Office of Dietary Supplements, Conference on Dietary Supplements, Coagulation, and Antithrombotic Therapies, Masur Auditorium, Clinical Center, NIH, January 13-14, 2005, Bethesda, MD.
Borgert CJ. 2004. Synergism, Antagonism, or Additivity of Dietary Supplements. Presentation for National Capitol Areas Society of Toxicology and National Capitol Area Society for Risk Analysis Fall Symposium, Lister Hill Auditorium, NIH, November 2, 2004, Bethesda, MD.
Borgert CJ. 2003. Update: CDC’s National Report on Human Exposure to Environmental Chemicals. Presentation for The Toxicology Forum, Summer Meeting. July 14, 2003, Aspen, Colorado.
Casella G. 2002. Statistical Issues in microarray experiments. Presented at the Universidad Rey Juan Carlos November 8, 2002, Madrid, Spain and at the University of Florida September 3, 2002, Gainesville, FL.
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Borgert CJ, Sargent EV, Casella G, Dietrich DR, McCarty LS, Golden RJ. The human relevant potency threshold: reducing uncertainty by human calibration of cumulative risk assessments. Regulatory Toxicology and Pharmacology (in press, October 28, 2011)
Borgert CJ, Mihaich EM, Ortego LS, Bentley KS, Holmes CM, Levine SL, Becker RA. 2011. Hypothesis-driven weight of evidence framework for evaluating data within the U. S. EPA’s Endocrine Disruptor Screening Program. Regulatory Toxicology and Pharmacology 61:185-191.
Borgert CJ, Mihaich EM, Quill TF, Marty MS, Levine SL, Becker RA. 2011. Evaluation of EPA’s Tier 1 Endocrine Screening Battery and recommendations for improving the interpretation of screening results. Regulatory Toxicology and Pharmacology 59:387-411.
Borgert CJ. 2007. Predicting interactions from mechanistic information: can omic data validate theories? Toxicology and Applied Pharmacology, 223(2):114-120.
Borgert, CJ. 2007. Conflict of interest or contravention of science? Regulatory Toxicology and Pharmacology 48(1):4-5.
Mason AM, Borgert CJ, Bus JM, Mumtaz MM, Simmons JE, Sipes IG. 2007. Improving the scientific foundation for mixtures joint toxicity and risk assessment: Contributions from the SOT mixtures project Introduction. Toxicology and Applied Pharmacology, 223(2):99-103.
Johnson KG, Muller JK, Price B, Ware A, Sepúlveda MS, Borgert CJ, and Gross TS. 2007. Influence of seasonality on the accumulation and reproductive effects of p,p¹-dichlorodiphenyldichloroethane and dieldrin in largemouth bass. Environmental Toxicology and Chemistry, 26(5): 927-934.
Muller, J.K., Scarborough, J.E., Sepulveda, M.S., Casella, G., Gross, T.S., and Borgert, C.J. 2007. Dose verification after topical treatment of alligator (Alligator Mississippiensis) eggs. Environmental Toxicology and Chemistry, 26(5): 908-913.
Muller, J.K., Gross, T.S., and Borgert, C.J. 2007. Topical dose delivery in the reptilian egg treatment model. Environmental Toxicology and Chemistry, 26(5): 914-919.
Findley KC, Borgert CJ. Evaluation of a novel relative potency approach for an herbal dietary supplement. 2007. The Toxicologist 96(1): 315
Ulloa S, Findley KC, Casella G, Borgert CJ. 2007. Evaluation of adverse event sampling bias. The Toxicologist 96(1): 198
Borgert, CJ. 2007. Letter to the Editor. Conflict of interest: Kill the messenger or follow the data?
Environmental Science & Technology 41(3): 665.
Borgert, CJ. 2007. Predicting interactions from mechanistic information: can omic data validate theories? Toxicology and Applied Pharmacology, Article in Press, Available online 12 January 2007.
Borgert CJ, Findley KC, Ulloa S, & Casella G. 2006. Dietary supplements and drug interactions: should flawed study designs and biased adverse event reporting affect regulation and medical causation? HarrisMartin’s Columns-Drugs & Supplements. July:1-5.
McCarty LS, & Borgert CJ. 2006. Review of the toxicity of chemical mixtures containing at least one organochlorine. Regulatory Toxicology and Pharmacology 45(2): 104-118.
McCarty LS, & Borgert CJ. 2006. Review of the toxicity of chemical mixtures: Theory, policy, and regulatory practice. Regulatory Toxicology and Pharmacology 45(2): 119-143.
Borgert CJ. 2005. Understanding human biomonitoring: workshop report. 2005 Regulatory Toxicology and Pharmacology 43:215-218.
Borgert CJ. 2005. EPA's new guidance for assessing cancer risks from early life exposures; genotoxic mode of action and implications for human health-based standards: a workshop's report. Regulatory Toxicology and Pharmacology 42:245-248
Borgert CJ, Borgert SA, Findley KC. 2005. Synergism, antagonism, or additivity of dietary supplements: application of theory to case studies. Thrombosis Research 117:123-132.
Borgert CJ. 2004. Chemical mixtures: an unsolvable riddle? Human and Ecological Risk Assessment, 10(4):619-629.
Borgert CJ, Quill TF, McCarty LS, Mason AM. 2004. Can mode of action predict mixtures toxicity for risk assessment? Toxicol. Appl. Pharmacol. Vol 201(2): 85-96.
Borgert CJ, Gross TS, Guiney PD, Osimitz TG, Price B, Wells C. 2004. Interactive effects of DDE and methoxychlor on hormone production in bass gonadal cultures. Environmental Toxicology Chemistry 23(8): 1947–1956.
Borgert CJ, LaKind JS, Witorsch RJ. 2003. A critical review of methods for comparing estrogenic activity of endogenous and exogenous chemicals in human milk and infant formula. Environmental Health Perspectives 111(8): 1020-1036.
LaKind JS, Birnbach N, Borgert CJ, Sonawane BR, Tully MR, Friedman L. 2002. Human milk surveillance and research of environmental chemicals: Concepts for consideration in interpreting and presenting study results. Journal of Toxicology and Environmental Health Part A. 65: 1909-28.
Berlin CM, LaKind JS, Sonawane BR, Kacew S, Borgert CJ, et al. 2002. Conclusions, research needs, and recommendations of the expert panel: technical workshop on human milk surveillance and research for environmental chemicals in the United States. Journal of Toxicology and Environmental Health Part A. 65: 1929-35.
Ma C-X, Casella G, & Wu R. 2002. Functional mapping of quantitative trait loci underlying the character process: a theoretical framework. Genetics. 161: 1751-1762.
Price B, Borgert CJ, Wells C, & Simon GS. 2002. Assessing toxicity of mixtures: the search for economical study designs. Human and Ecological Risk Assessment, 8(2): 305-326.
Wu R, Ma C-X, & Casella G. 2002. Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations. Genetics. 160: 779-792.
Borgert CJ, Price B, Wells C, & Simon GS. 2001. Evaluating interaction studies for mixture risk assessment. Human and Ecological Risk Assessment, 7(2): 259-306.
Casella G. 2001. Empirical Bayes Gibbs sampling. Biostatistics. 2(4): 485-500.
Borgert CJ, Roberts SM, Harbison RD, James RC. 1995. Influence of soil half-life on risk assessment of carcinogens. Regulatory Toxicology and Pharmacology. 22: 143-151.
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